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Home » Recipes » Dinner Recipes

John Wayne Casserole


Prep Time :15 minutes mins
Cook Time :35 minutes mins
Total Time :50 minutes mins
Servings :8
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A dished out serving of John wayne casserole recipe, cropped square.
A collage of two images , one full dish view of a John wayne casserole with a serving missing, and the other a dished up serving of the casserole. There's some text overlay for pinterest.

Published: Feb 28, 2023 · Modified: Aug 15, 2024 by Melanie Cagle · 2 Comments

A John Wayne Casserole is a western flavored casserole full of amazing spices and textured layers. Everyone in the family will love this beef and biscuit casserole recipe.

A side view of a John Wayne Casserole with a spooned serving missing.
John Wayne Casserole
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It's a cool story. Apparently, John Wayne did contribute a recipe directly to a cookbook named "Cooking with love, from Cara and her friends" (Cara Connery). This was back in 1979.

The original recipe was made up of eggs and cheese.

There was a cafeteria in a medical center in Mississippi that created a different version - adding ground beef, biscuits and peppers.

It became a very popular version and in no time the recipe spread.

Jump to:
  • What makes this recipe so yummy
  • Groceries you'll need: Ingredients
  • Recipe walkthrough: Instructions
  • Recipe variations and substitute ideas
  • Necessary gear: Equipment
  • More casserole recipes I think you'll love
  • How to store leftovers
  • Mel's kitchen notes
  • Frequently asked questions: FAQs
  • John Wayne Casserole
  • 💬 Comments

What makes this recipe so yummy

  • The different textures are fabulous. From the firmness of the biscuit crust layer to the ooey-gooeyness of the cheese layer and all that tasty meat and peppers in-between.
  • The ingredients are not fancy or difficult to find. It's an easy recipe.
  • It's a casserole recipe that the whole family will love.

Groceries you'll need: Ingredients

Ingredients needed to make a John Wayne Casserole.
  • Bisquick biscuit mix
  • Water
  • Ground Beef
  • Taco Seasoning
  • Canned Tomatoes and Chilies
  • Bell Peppers
  • Yellow Onion
  • Jalapeño Peppers
  • Cream Cheese
  • Mayonnaise
  • Colby Cheese

See recipe card at the bottom of this post for quantities.

Recipe walkthrough: Instructions

This is an overview of the recipe steps. For more detailed instructions visit the recipe card at the bottom of this post.

A collage of four images showing how to make a John Wayne Casserole, steps 1 through 4.
  • Step 1: Mix the bisquick with water and add to a casserole dish. Bake for 15 minutes.
  • Step 2: While that layer is baking brown the ground beef until no pink remains.
  • Step 3: Add the taco seasoning and water and cook 5 minutes.
  • Step 4: Using a slotted spoon layer on top of the biscuit layer.
A collage of four images showing how to make a John Wayne Casserole with Bisquick recipe, steps 5-8.
  • Step 5: Add the bell peppers, onions and tomatoes and chilies to the same skillet and cook until soft.
  • Step 6: Layer on top of the taco meat mixture.
  • Step 7: In a medium mixing bowl add the softened cream cheese, mayonnaise and half of the cheese. Mix well.
  • Step 8: Spread on top of the bell pepper mixture.
A collage of two images showing how to make a John Wayne Casserole.
  • Step 9: Layer some sliced jalapeno peppers on top then sprinkle with remaining cheese.
  • Step 10: Bake in the oven for 35 minutes.

Hint: I like to use the original version of Rotel for this recipe. There's also a mild version and a hot version. You could change this up for added/less heat.

Recipe variations and substitute ideas

  • Sour Cream - instead of cream cheese.
  • Green Peppers - use green bell peppers as well.
  • Green Chilies - instead of the tomatoes, use these with fresh tomatoes.
  • Ground Turkey - instead of ground beef.
  • Tater Tots - instead of the biscuit layer.
  • Pepper Jack Cheese - instead of the Colby - or maybe Colby Jack cheese.
  • Black Olives - add to the bell peppers layer.
  • Green Onions - sprinkle some on top.
  • Garlic Powder - add a touch to the cheese mixture on top.
Overhead shot of a baked John Wayne Casserole with bisquick recipe.

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Necessary gear: Equipment

The following are affiliate links. We are a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for us to earn fees by linking to Amazon.com and affiliated sites.

I used a 13x9" Casserole Dish, a large 12" skillet and a mixing bowl.

I have some affiliate links in the recipe card below.

More casserole recipes I think you'll love

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  • Big Mac Casserole
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  • Jalapeno Popper Tater Tot Casserole

You could also try my Crock Pot Pinto Beans recipe, for a great Western flavored dish. Then finish it up with my yummy Snickers Bar Brownies.

How to store leftovers

Once the John Wayne Casserole has cooled completely cover with plastic wrap or aluminum foil (or transfer to an airtight container) and store in the refrigerator for up to 4 days.

It does in fact freeze well if you want to do that too. Store in a freezer safe container and freeze for up to 3 months.

Mel's kitchen notes

This is one of those dishes that actually tastes best the next day.

A serving of John Wayne Casserole with bisquick recipe on a plate.

Frequently asked questions: FAQs

Why Is It Called John Wayne Casserole?

John Wayne actually contributed a recipe to a cookbook back in 1979 - although quite different to this version. It was adapted by a cafeteria whose recipe became famous.


If you’ve tried this John Wayne Casserole Recipe or any other great recipe on my site, let me know in the comment section below, how it turned out, we love hearing from our readers!

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A dished out serving of John wayne casserole recipe, cropped square.
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John Wayne Casserole

A western inspired dish full of flavor, John Wayne Casserole has a Tex-Mex like flavor profile, with delicious layers.
Prep Time15 minutes mins
Cook Time35 minutes mins
Total Time50 minutes mins
Servings: 8
Cuisine: American
Author: Melanie Cagle
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Equipment

  • 13 Inch Enameled Cast Iron Baking Dish

Ingredients

  • 2 Cups Bisquick Pancake Mix
  • 1-½ Cups Water divided
  • 2 Pounds Ground Beef
  • 2 (1 Ounce) Packs Taco Seasoning
  • 1 (10 Ounce) Can Diced Tomatoes and Chilies
  • 1 Each Red Bell Pepper diced
  • 1 Each Yellow Bell Pepper diced
  • 1 Each Yellow Onions diced
  • ½ Cup Mayonnaise
  • 1 (8 Ounce) Block Cream Cheese softened
  • 2 Cups Colby Cheese grated, divided
  • 1 Each Jalapeno Peppers sliced

Instructions

  • Preheat the oven to 350°F.
  • Mix the bisquick with 1 cup of water. Pour into a 9x13" Casserole dish, sprayed with cooking spray.
    2 Cups Bisquick Pancake Mix, 1-½ Cups Water
  • Bake in the oven for 15 minutes then remove.
  • While the biscuit layer is baking add the ground beef to a large skillet and brown until no pink remains.
    2 Pounds Ground Beef
  • Add the taco seasoning and remaining ½ cup water. Cook for 5 minutes.
    2 (1 Ounce) Packs Taco Seasoning, 1-½ Cups Water
  • Spoon over the top of the biscuit layer using a slotted spoon, pushing down if necessary.
  • Discard the grease that's left then add the diced onion, bell peppers and tomatoes and chilies to the same skillet. Cook until softened.
    1 (10 Ounce) Can Diced Tomatoes and Chilies, 1 Each Red Bell Pepper, 1 Each Yellow Bell Pepper, 1 Each Yellow Onions
  • Layer on top of the taco meat.
  • In a mixing bowl add the cream cheese, mayonnaise and 1 cup of cheese and mix well.
    ½ Cup Mayonnaise, 1 (8 Ounce) Block Cream Cheese, 2 Cups Colby Cheese
  • Spread over the top of the bell pepper mixture, evenly.
  • Add some slices of jalapeno then sprinkle the remaining cheese over the top.
    1 Each Jalapeno Peppers, 2 Cups Colby Cheese
  • Bake in the oven for 35 minutes, until bubbly around the edges.
  • Remove and allow to rest for 5 minutes then serve.
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Nutrition

Serving: 1g | Calories: 643kcal | Carbohydrates: 7g | Protein: 41g | Fat: 50g | Saturated Fat: 21g | Polyunsaturated Fat: 24g | Trans Fat: 1g | Cholesterol: 164mg | Sodium: 520mg | Fiber: 1g | Sugar: 3g

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Filed Under: Beef Recipes, Casseroles, Dinner Recipes, Lunch Recipes, Southern Recipes, Weeknight Recipes

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  1. SADIE WEATHERS says

    April 16, 2023 at 6:53 pm

    I made it!!! It's delicious!

    Reply
    • Melanie Cagle says

      April 16, 2023 at 7:11 pm

      So glad you enjoyed it Sadie!

      Reply

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